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Patients all over the world can use this page for sending your questions on diabetes, asthma and geriatric illnesses.
Registered Patients
Dr.Christopher Saudek, Director Johns Hopkins Diabetes Center, Baltimore, USA (American Diabetes Association President 2002) during his visit to India was with Diabscreen Kerala for 2 hours on Feb. 03, 2006 from 4.00 pm IST. Dr CD Saudek made a fantastic lecture........ more
Aug 12: Diabscreen CME for doctors - Incretins and DPP4 inhibitors.

Dr.Jothydev talks on Incretins and DPP-4 inhibitors.
Dr.Manoj kumar on Periarthritis in Diabetes.
Introduction: Dr.Sabeer A Rasheed
Chair: Dr.Madusudhanan

Venue: Residency towers

Incretins and DPP4 inhibitors.

Incretins are gut hormones which stimulate pancreas to produce insulin. Exenatide(twice daily) and Liraglutide(once daily) are the two incretins to be used as injections for the treatment of Type 2 DM. Both apart from blood glucose reduction will also inhibit post meal glucagon production and will also produce weight loss. GLP-1 is a the major target of therapy for the future. However GLP-1 is rapidly degraded by DPP-4(Dipeptidyl peptidase 4)

DPP-4 inhibitors can increase active GLP-1 pool in the blood. DPP4 inhibitors soon to be in the market are Vildagliptin and Sitagliptin. Both are oral drugs with minimal adverse effects and produce no weight gain.

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